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05-Nov-2019 18:11

Smokers The starting dose and dose range need not be routinely altered for non- smokers relative to smokers.The metabolism of olanzapine may be induced by smoking.

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In patients whose manic episode has responded to Olanzapine Accord treatment, Olanzapine Accord is indicated for the prevention of recurrence in patients with bipolar disorder (see section 5.1).If a new manic, mixed, or depressive episode occurs, Olanzapine Accord treatment should be continued (with dose optimization as needed), with supplementary therapy to treat mood symptoms, as clinically indicated.